Defining the Cardiac Fibroblast
نویسندگان
چکیده
منابع مشابه
Cardiac fibroblast: the renaissance cell.
The permanent cellular constituents of the heart include cardiac fibroblasts, myocytes, endothelial cells, and vascular smooth muscle cells. Previous studies have demonstrated that there are undulating changes in cardiac cell populations during embryonic development, through neonatal development and into the adult. Transient cell populations include lymphocytes, mast cells, and macrophages, whi...
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Cardiac fibrosis is a serious condition currently lacking effective treatments. It occurs as a result of cardiac fibroblast (CFB) activation and differentiation into myofibroblasts, characterized by proliferation, extracellular matrix (ECM) production and stiffening, and contraction due to the expression of smooth muscle α-actin. The mechanical properties of myocardium change regionally and ove...
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ژورنال
عنوان ژورنال: Circulation Journal
سال: 2016
ISSN: 1346-9843,1347-4820
DOI: 10.1253/circj.cj-16-1003